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Adeno-associated Virus Vector Serotypes Mediate Sustained Correction of Bilirubin UDP Glucuronosyltransferase Deficiency in Rats

  • Published:2006-06 Issue:6 Volume:13 Page:1085-1092
  • ISSN:1525-0016
  • Container-title:Molecular Therapy
  • language:en
  • Short-container-title:Molecular Therapy

Author:

Seppen Jurgen,Bakker Conny,de Jong Berry,Kunne Cindy,van den Oever Karin,Vandenberghe Kristin,de Waart Rudi,Twisk Jaap,Bosma Piter

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference38 articles.

1. Structure and binding of unconjugated bilirubin: relevance for physiological and pathophysiological function;Ostrow;J. Lipid Res.,1994

2. Human UDP-glucuronosyltransferases: metabolism, expression, and disease;Tukey;Annu. Rev. Pharmacol. Toxicol.,2000

3. Diagnosis and management of Crigler–Najjar syndrome;Jansen;Eur. J. Pediatr.,1999

4. Mechanisms of bilirubin neurotoxicity;Ostrow;Hepatology,2002

5. Gunn rat: a model for inherited deficiency of bilirubin glucuronidation;Chowdhury;Adv. Vet. Sci. Comp. Med.,1993

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