Long-term Transgene Expression from Plasmid DNA Gene Therapy Vectors Is Negatively Affected by CpG Dinucleotides-Reference-Cited by-同舟云学术

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Long-term Transgene Expression from Plasmid DNA Gene Therapy Vectors Is Negatively Affected by CpG Dinucleotides

Published:2004-08 Issue:2 Volume:10 Page:269-278
ISSN:1525-0016
Container-title:Molecular Therapy
language:en
Short-container-title:Molecular Therapy

Author:

Hodges Bradley L.,Taylor Kristin M.,Joseph Macy F.,Bourgeois Sarah A.,Scheule Ronald K.

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference53 articles.

1. Gene silencing as a threat to the success of gene therapy;Bestor;J. Clin. Invest,2000

2. Long-term expression of human alpha1-antitrypsin gene in mouse liver achieved by intravenous administration of plasmid DNA using a hydrodynamics-based procedure;Zhang;Gene Ther,2000

3. Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA;Liu;Gene Ther,1999

4. Time course of gene expression after plasmid DNA gene transfer to the liver;Herweijer;J. Gene Med,2001

5. Reduced inflammatory response to plasmid DNA vectors by elimination and inhibition of immunostimulatory CpG motifs;Yew;Mol. Ther,2000

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