APOE2 gene therapy reduces amyloid deposition and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer disease-Reference-Cited by-同舟云学术

APOE2 gene therapy reduces amyloid deposition and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer disease

Published:2024-05 Issue:5 Volume:32 Page:1373-1386
ISSN:1525-0016
Container-title:Molecular Therapy
language:en
Short-container-title:Molecular Therapy

Author:

Jackson Rosemary J.^ORCID,Keiser Megan S.,Meltzer Jonah C.,Fykstra Dustin P.,Dierksmeier Steven E.,Hajizadeh Soroush,Kreuzer Johannes,Morris Robert,Melloni Alexandra,Nakajima Tsuneo,Tecedor Luis,Ranum Paul T.,Carrell Ellie,Chen YongHong,Nishtar Maryam A.,Holtzman David M.,Haas Wilhelm,Davidson Beverly L.,Hyman Bradley T.

Funder

JPB Foundation

THE CHILDRENS HOSPITAL OF PHILADELPHIA

NIH

Publisher

Elsevier BV

Reference45 articles.

1. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer’s disease in late onset families;Corder;Science,1993

2. Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease;Corder;Nat. Genet.,1994

3. Apolipoprotein E in sporadic Alzheimer’s disease: Allelic variation and receptor interactions;Rebeck;Neuron,1993

4. Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study;Reiman;Nat. Commun.,2020

5. Frequency of the apolipoprotein E epsilon 2 allele is diminished in sporadic Alzheimer disease;West;Neurosci. Lett.,1994

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Emerging paradigms in Alzheimer's therapy;European Journal of Pharmacology;2024-10

2. Pathways to personalized medicine—Embracing heterogeneity for progress in clinical therapeutics research in Alzheimer's disease;Alzheimer's & Dementia;2024-09-06

3. Updates in Alzheimer's disease: from basic research to diagnosis and therapies;Translational Neurodegeneration;2024-09-04

4. New insights into innate immunity in Alzheimer’s disease: from APOE protective variants to therapies;Trends in Immunology;2024-09

5. Emerging Gene Therapies for Alzheimer’s and Parkinson’s Diseases: An Overview of Clinical Trials and Promising Candidates;Cureus;2024-08-16