A New Promoter Allows Optogenetic Vision Restoration with Enhanced Sensitivity in Macaque Retina

Author:

Chaffiol Antoine,Caplette Romain,Jaillard Céline,Brazhnikova Elena,Desrosiers Mélissa,Dubus Elisabeth,Duhamel Laëtitia,Macé Emilie,Marre Olivier,Benoit Patrick,Hantraye Philippe,Bemelmans Alexis-Pierre,Bamberg Ernst,Duebel Jens,Sahel José-Alain,Picaud Serge,Dalkara Deniz

Funder

Sanofi

INSERM

UPMC

CNRS

Fondation pour la Recherche Medicale

Agence Nationale pour la Recherche Investissements d’Avenir Recherche Hospitalo-Univesritaire en santé

RHU

E-Rare Project

OPTOREMODE

Foundation Fighting Blindness

Fédération des Aveugles de France

City of Paris

Regional Council of Ile-de-France

Agence Nationale de la Recherche

European Research Council

ERC

Deutsche Forschungsgemeinschaft

Max Planck Society

NIH

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference54 articles.

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2. Photoreceptor degeneration: genetic and mechanistic dissection of a complex trait;Wright;Nat. Rev. Genet.,2010

3. Morphometric analysis of the extramacular retina from postmortem eyes with retinitis pigmentosa;Humayun;Invest. Ophthalmol. Vis. Sci.,1999

4. Interim results from the international trial of Second Sight’s visual prosthesis;Humayun;Ophthalmology,2012

5. Retinal optogenetic therapies: clinical criteria for candidacy;Jacobson;Clin. Genet.,2013

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