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TET-dependent GDF7 hypomethylation impairs aqueous humor outflow and serves as a potential therapeutic target in glaucoma

  • Published:2021-04 Issue:4 Volume:29 Page:1639-1657
  • ISSN:1525-0016
  • Container-title:Molecular Therapy
  • language:en
  • Short-container-title:Molecular Therapy

Author:

Wan Peixing,Long Erping,Li Zhidong,Zhu Yingting,Su Wenru,Zhuo Yehong

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference65 articles.

1. Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis;Tham;Ophthalmology,2014

2. Primary open-angle glaucoma;Kwon;N. Engl. J. Med.,2009

3. The aqueous humor outflow pathways in glaucoma: A unifying concept of disease mechanisms and causative treatment;Braunger;Eur. J. Pharm. Biopharm.,2015

4. Family history and risk of primary open angle glaucoma. The Baltimore Eye Survey;Tielsch;Arch. Ophthalmol.,1994

5. Inherited, familial and sporadic primary open-angle glaucoma;Gong;J. Natl. Med. Assoc.,2007
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