Vector genome loss and epigenetic modifications mediate decline in transgene expression of AAV5 vectors produced in mammalian and insect cells-Reference-Cited by-同舟云学术

Vector genome loss and epigenetic modifications mediate decline in transgene expression of AAV5 vectors produced in mammalian and insect cells

Published:2022-12 Issue:12 Volume:30 Page:3570-3586
ISSN:1525-0016
Container-title:Molecular Therapy
language:en
Short-container-title:Molecular Therapy

Author:

Handyside Britta,Ismail Ashrafali Mohamed,Zhang Lening,Yates Bridget,Xie Lin,Sihn Choong-Ryoul,Murphy Ryan,Bouwman Taren,Kim Chan Kyu,De Angelis Rolando,Karim Omair A.,McIntosh Nicole L.,Doss Michael Xavier,Shroff Shilpa,Pungor Erno,Bhat Vikas S.,Bullens Sherry,Bunting Stuart,Fong Sylvia^ORCID

Funder

BioMarin Pharmaceutical

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

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