Synergy of Immune Checkpoint Blockade with a Novel Synthetic Consensus DNA Vaccine Targeting TERT

Author:

Duperret Elizabeth K.,Wise Megan C.,Trautz Aspen,Villarreal Daniel O.,Ferraro Bernadette,Walters Jewell,Yan Jian,Khan Amir,Masteller Emma,Humeau Laurent,Weiner David B.

Funder

NIH/NCI NRSA

Penn/Wistar Institute NIH SPORE

Wistar National Cancer Institute Cancer Center

W.W. Smith Family Trust

Basser Foundation

Inovio Pharmaceuticals

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference47 articles.

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3. CTLA-4 regulates tolerance induction and T cell differentiation in vivo;Walunas;J. Immunol.,1998

4. Tim-3: an emerging target in the cancer immunotherapy landscape;Anderson;Cancer Immunol. Res.,2014

5. Dual blockade of PD-1 and CTLA-4 combined with tumor vaccine effectively restores T-cell rejection function in tumors;Duraiswamy;Cancer Res.,2013

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