Pyridazine based inhibitors of p38 MAPK

Author:

McIntyre Charles J,Ponticello Gerald S,Liverton Nigel J,O’Keefe Stephen J,O’Neill Edward A,Pang Margaret,Schwartz Cheryl D,Claremon David A

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference23 articles.

1. Design and Synthesis of Potent, Selective, and Orally Bioavailable Tetrasubstituted Imidazole Inhibitors of p38 Mitogen-Activated Protein Kinase

2. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

3. Lee, J. C.; Young, P. R. J. Leuk. Bio. 1996, 59, 152.

4. Wang, H.; Tracey, K. J. In Inflammation: Basic Principles and Clinical Correlates, 3rd ed.; Gallin, J. I., Snyderman, R., Eds.; Lippincott, Williams & Wilkins: Philadelphia, 1999; p 471.

5. Physicians Desk Reference, 54th ed.; Medical Economics: Montvale, 2000; pp 927 and 1413.

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