Selective Inhibition of Src SH2 by a Novel Thiol-Targeting Tricarbonyl-Modified Inhibitor and Mechanistic Analysis by 1H/13C NMR Spectroscopy-Reference-Cited by-同舟云学术

Selective Inhibition of Src SH2 by a Novel Thiol-Targeting Tricarbonyl-Modified Inhibitor and Mechanistic Analysis by 1H/13C NMR Spectroscopy

Published:2001-07 Issue:13 Volume:11 Page:1665-1669
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Sundaramoorthi Raji,Siedem Chris,Vu Chi B,Dalgarno David C,Laird Ellen C,Botfield Martyn C,Combs Amanda B,Adams Susan E,Yuan Ruth W,Weigele Manfred,Narula Surinder S

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference22 articles.

1. SH2 domains recognize specific phosphopeptide sequences

2. CELLULAR FUNCTIONS REGULATED BY SRC FAMILY KINASES

3. Protein modules and signalling networks

4. Modular binding domains in signal transduction proteins

5. Src homology-2 domains: Structure, mechanisms, and drug discovery

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