CCR5 antagonists: bicyclic isoxazolidines as conformationally constrained N-1-substituted pyrrolidines-Reference-Cited by-同舟云学术

CCR5 antagonists: bicyclic isoxazolidines as conformationally constrained N-1-substituted pyrrolidines

Published:2002-02 Issue:4 Volume:12 Page:677-679
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Lynch Christopher L,Gentry Amy L,Hale Jeffrey J,Mills Sander G,MacCoss Malcolm,Malkowitz Lorraine,Springer Martin S,Gould Sandra L,DeMartino Julie A,Siciliano Salvatore J,Cascieri Margaret A,Doss George,Carella Anthony,Carver Gwen,Holmes Karen,Schleif William A,Danzeisen Renee,Hazuda Daria,Kessler Joseph,Lineberger Janet,Miller Michael,Emini Emilio A

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference14 articles.

1. Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

2. A Conserved HIV gp120 Glycoprotein Structure Involved in Chemokine Receptor Binding

3. CHEMOKINE RECEPTORS AS HIV-1 CORECEPTORS: Roles in Viral Entry, Tropism, and Disease

4. Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

5. A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity

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