Design, synthesis and evaluation of substituted phenylpropanoic acid derivatives as peroxisome proliferator-activated receptor (PPAR) activators: novel human PPARα-selective activators-Reference-Cited by-同舟云学术

Design, synthesis and evaluation of substituted phenylpropanoic acid derivatives as peroxisome proliferator-activated receptor (PPAR) activators: novel human PPARα-selective activators

Published:2002-01 Issue:1 Volume:12 Page:77-80
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Miyachi Hiroyuki,Nomura Masahiro,Tanase Takahiro,Takahashi Yukie,Ide Tomohiro,Tsunoda Masaki,Murakami Koji,Awano Katsuya

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference19 articles.

1. Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors

2. Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers.

3. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

4. Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators.

Cited by 46 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Tetrafluoroisopropylation of alkenes and alkynes enabled by photocatalytic consecutive difluoromethylation with CF2HSO2Na;Nature Communications;2024-07-06

2. Comorbidities confound metabolomics studies of human disease;2024-06-04

3. Modulation of PPAR signaling disrupts pancreas development in the zebrafish, Danio rerio;Toxicology and Applied Pharmacology;2021-09

4. Structural Biology-Based Exploration of Subtype-Selective Agonists for Peroxisome Proliferator-Activated Receptors;International Journal of Molecular Sciences;2021-08-26

5. PPARα and δ Ligand Design: Honing the Traditional Empirical Method with a More Holistic Overview;Nuclear Receptors;2021