Discovery and initial SAR of imidazoquinoxalines as inhibitors of the Src-family kinase p56Lck-Reference-Cited by-同舟云学术

Discovery and initial SAR of imidazoquinoxalines as inhibitors of the Src-family kinase p56Lck

Published:2002-05 Issue:10 Volume:12 Page:1361-1364
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Chen Ping,Norris Derek,Iwanowicz Edwin J.,Spergel Steven H.,Lin James,Gu Henry H.,Shen Zhongqi,Wityak John,Lin Tai-An,Pang Suhong,De Fex Henry F.,Pitt Sidney,Shen Ding Ren,Doweyko Arthur M.,Bassolino Donna A.,Roberge Jacques Y.,Poss Michael A.,Chen Bang-Chi,Schieven Gary L.,Barrish Joel C.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference30 articles.

1. Profound block in thymocyte development in mice lacking p56lck

2. A dominant-negative transgene defines a role for p56lck in thymopoiesis.

3. Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

4. The Role of Protein Tyrosine Kinases and Protein Tyrosine Phosphatases in T Cell Antigen Receptor Signal Transduction

5. Signal transduction by lymphocyte antigen receptors

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