Synthesis and antiviral activity of a novel class of HIV-1 protease inhibitors containing a heterocyclic P1′-P2′ amide bond isostere-Reference-Cited by-同舟云学术

Synthesis and antiviral activity of a novel class of HIV-1 protease inhibitors containing a heterocyclic P1′-P2′ amide bond isostere

Published:1994-10 Issue:20 Volume:4 Page:2441-2446
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Thompson Scott K.,Eppley Alecia M.,Frazee James S.,Darcy Michael G.,Lum Robert T.,Tomaszek Thaddeus A.,Ivanoff Lucinda A.,Morris Jane F.,Sternberg Edmund J.,Lambert Dennis M.,Fernandez Annabellee V.,Petteway Stephen R.,Meek Thomas D,Metcalf Brian W.,Gleason John G.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference24 articles.

1. AIDS in 1988

2. HTLV-III gag Protein Is Processed in Yeast Cells by the Virus pol -Protease

3. Active human immunodeficiency virus protease is required for viral infectivity.

4. Inhibitors of Aspartyl Proteinases

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