3,4-diarylpyrazoles: Potent and selective inhibitors of cyclooxygenase-2-Reference-Cited by-同舟云学术

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3,4-diarylpyrazoles: Potent and selective inhibitors of cyclooxygenase-2

Published:1997-08 Issue:16 Volume:7 Page:2121-2124
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Penning Thomas D.,Kramer Steven W.,Lee Len F.,Collins Paul W.,Koboldt Carol M.,Seibert Karen,Veenhuizen Amy W.,Zhang Yan Y.,Isakson Peter C.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference13 articles.

1. Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs

2. Gastrointestinal Damage Associated with the Use of Nonsteroidal Antiinflammatory Drugs

3. Synthesis and Biological Evaluation of the 1,5-Diarylpyrazole Class of Cyclooxygenase-2 Inhibitors: Identification of 4-[5-(4-Methylphenyl)-3- (trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide (SC-58635, Celecoxib)

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1. Effective Synthesis of N-Alkyl-3-(Indol-3-yl)Pyrazoles from Ag₂CO₃- Catalyzed Regioselective Aza-Michael Addition of 5-(Indol-3-yl)-1HPyrazoles;Letters in Organic Chemistry;2024-10

2. Regioselective Synthesis of Isomeric 3-[1-Substituted Pyrazol-3(5)-yl]indoles from β-Ethylthio-β-indolyl-α,β-unsaturated Ketones;Synthesis;2020-03-30

3. Classification of Cyclooxygenase-2 Inhibitors Using Support Vector Machine and Random Forest Methods;Journal of Chemical Information and Modeling;2019-02-14

4. SAR and QSAR models of cyclooxygenase-1 (COX-1) inhibitors;SAR and QSAR in Environmental Research;2018-10-02

5. Radical Addition of Hydrazones by α-Bromo Ketones To Prepare 1,3,5-Trisubstituted Pyrazoles via Visible Light Catalysis;The Journal of Organic Chemistry;2016-07-14

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