Synthesis of 3-phenylpyrazolo[4,3-b]pyridines via a convenient synthesis of 4-amino-3-arylpyrazoles and SAR of corticotropin-Releasing factor receptor type-1 antagonists-Reference-Cited by-同舟云学术

Synthesis of 3-phenylpyrazolo[4,3-b]pyridines via a convenient synthesis of 4-amino-3-arylpyrazoles and SAR of corticotropin-Releasing factor receptor type-1 antagonists

Published:2003-10 Issue:19 Volume:13 Page:3367-3370
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Wilcoxen Keith,Huang Charles Q,McCarthy James R,Grigoriadis Dimitri E,Chen Chen

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference23 articles.

1. CP-154,526: a potent and selective nonpeptide antagonist of corticotropin releasing factor receptors.

2. Wilcoxen, K.; Chen, C.; Huang, C.; Haddach, M.; Xie, M.; Wing, L.; Grigoriadis, D. E.; De Souza, E. B.; McCarthy, J. R. Book of Abstracts, 217th American Chemical Society National Meeting, Anaheim, CA, USA, March 21–25, 1999; MEDI 002.

3. Pyrazolo[1,5-a]pyrimidine CRF-1 receptor antagonists

4. The discovery of 4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)-pyrazolo-[1,5- a ]-pyrimidine: A corticotropin-releasing factor (hCRF 1 ) antagonist

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