Potent quinoxaline-Based inhibitors of PDGF receptor tyrosine kinase activity. Part 2: the synthesis and biological activities of RPR127963 an orally bioavailable inhibitor-Reference-Cited by-同舟云学术

Potent quinoxaline-Based inhibitors of PDGF receptor tyrosine kinase activity. Part 2: the synthesis and biological activities of RPR127963 an orally bioavailable inhibitor

Published:2003-09 Issue:18 Volume:13 Page:3097-3100
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

He Wei,Myers Michael R.,Hanney Barbara,Spada Alfred P.,Bilder Glenda,Galzcinski Helen,Amin Dilip,Needle Saul,Page Ken,Jayyosi Zaid,Perrone Mark H.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference12 articles.

1. (a) He, W.; Myers, M. R.; Spada, A. P.; Hanney, B.; Setzer, N.; Mailliet, P.; Gontier, S.; Guegen, J.-C.; Cans, P.; Orton, E.; Cheve, M.; Kubiak, G. G.; Shah, H. C.; O'Brien, M. K.; Bilder, G. E.; Allen, E.; Bissery, M.-C.; Page, K.; Natarajan, C.; Jayyosi, Z.; Kelley, M. F.; Toutain, H.; Constan, A.; Amin, D.; Needle, S.; Galczenski, H.; Wang, W.; Perrone, M. H. Abstracts of Papers, 219th ACS National Meeting, San Francisco, CA, March 26–30, 2000; MEDI-307.

2. (b) Myers, M. R. The SCI-Fine Chemicals sponsored conference Protein Tyrosin Kinases, Good Targets for Drugs?, London, May 22, 2001.

3. Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor

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