Characterization of HERG potassium channel inhibition using CoMSiA 3D QSAR and homology modeling approaches-Reference-Cited by-同舟云学术

Characterization of HERG potassium channel inhibition using CoMSiA 3D QSAR and homology modeling approaches

Published:2003-05 Issue:10 Volume:13 Page:1829-1835
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Pearlstein Robert A,Vaz Roy J,Kang Jiesheng,Chen Xiao-Liang,Preobrazhenskaya Maria,Shchekotikhin Andrey E,Korolev Alexander M,Lysenkova Ludmila N,Miroshnikova Olga V,Hendrix James,Rampe David

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference27 articles.

1. HERG, a Primary Human Ventricular Target of the Nonsedating Antihistamine Terfenadine

2. A mechanism for the proarrhythmic effects of cisapride (Propulsid): high affinity blockade of the human cardiac potassium channel HERG

3. Block of HERG Potassium Channels by the Antihistamine Astemizole and its Metabolites Desmethylastemizole and Norastemizole

4. Three-Dimensional Quantitative Structure-Activity Relationship for Inhibition of Human Ether-a-Go-Go-Related Gene Potassium Channel

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