Potent HIV protease inhibitors incorporating high-affinity P2-ligands and (R)-(hydroxyethylamino)sulfonamide isostere-Reference-Cited by-同舟云学术

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Potent HIV protease inhibitors incorporating high-affinity P2-ligands and (R)-(hydroxyethylamino)sulfonamide isostere

Published:1998-03 Issue:6 Volume:8 Page:687-690
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Ghosh Arun K,Kincaid John F,Cho Wonhwa,Walters D.Eric,Krishnan K,Hussain Khaja Azhar,Koo Yumee,Cho Hanna,Rudall Clare,Holland Louis,Buthod Jim

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference21 articles.

1. Rational Design of Peptide-Based HIV Proteinase Inhibitors

2. Characterization of human immunodeficiency virus type 1 mutantswith decreased sensitivity to proteinase inhibitor Ro 31-8959

3. In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors

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3. An enzymatic route to the synthesis of tricyclic fused hexahydrofuranofuran P2-Ligand for a series of highly potent HIV-1 protease inhibitors;Tetrahedron Letters;2024-04

4. The Structure-property Relationships of Clinically Approved Protease Inhibitors;Current Medicinal Chemistry;2024-04

5. Machine learning‐guided design of potent darunavir analogs targeting HIV‐1 proteases: A computational approach for antiretroviral drug discovery;Journal of Computational Chemistry;2024-01-04

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