Rational design of boropeptide thrombin inhibitors: β,β-dialkyl-phenethylglycine P2 analogs of DuP 714 with greater selectivity over complement factor I and an improved safety profile-Reference-Cited by-同舟云学术

Rational design of boropeptide thrombin inhibitors: β,β-dialkyl-phenethylglycine P2 analogs of DuP 714 with greater selectivity over complement factor I and an improved safety profile

Published:1998-02 Issue:3 Volume:8 Page:301-306
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Fevig John M,Buriak Joseph,Cacciola Joseph,Alexander Richard S,Kettner Charles A,Knabb Robert M,Pruitt James R,Weber Patricia C,Wexler Ruth R

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference16 articles.

1. Thrombin active site inhibitors

2. The selective inhibition of thrombin by peptides of boroarginine.

3. In Vivo Characterization of a New Synthetic Thrombin Inhibitor

4. Book of Abstracts 212th ACS National Meeting;Kettner,1996

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