Cleavage of the cyclohexyl-subunit of rapamycin results in loss of immunosuppressive activity-Reference-Cited by-同舟云学术

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Cleavage of the cyclohexyl-subunit of rapamycin results in loss of immunosuppressive activity

Published:1999-02 Issue:3 Volume:9 Page:459-462
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Sedrani Richard,Jones Lyn H.,Jutzi-Eme Anne-Marie,Schuler Walter,Cottens Sylvain

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference14 articles.

1. Molecular mechanisms of action of new xenobiotic immunosuppressive drugs: tacrolimus (FK506), sirolimus (rapamycin), mycophenolate mofetil and leflunomide

2. Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

3. Atomic structure of the rapamycin human immunophilin FKBP-12 complex

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4. The influence of co-solvents on the stability and bioavailability of rapamycin formulated in self-microemulsifying drug delivery systems;Drug Development and Industrial Pharmacy;2011-03-21

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