N-[2-(1-cyclohexenyl)ethyl]-N′-[2-(5-bromopyridyl)]-thiourea and N′-[2-(1-cyclohexenyl)ethyl]-N′-[2-(5-chloropyridyl)]- thiourea as potent inhibitors of multidrug-resistant human immunodeficiency virus-1-Reference-Cited by-同舟云学术

N-[2-(1-cyclohexenyl)ethyl]-N′-[2-(5-bromopyridyl)]-thiourea and N′-[2-(1-cyclohexenyl)ethyl]-N′-[2-(5-chloropyridyl)]- thiourea as potent inhibitors of multidrug-resistant human immunodeficiency virus-1

Published:1999-09 Issue:18 Volume:9 Page:2721-2726
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Uckun Fatih M.,Mao Chen,Pendergrass Sharon,Maher Danielle,Zhu Dan,Tuel-Ahlgren Lisa,Venkatachalam T.K.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference10 articles.

1. Antiretroviral Therapy for HIV Infection in 1998

2. Phenethylthiazolethiourea (PETT) Compounds, a New Class of HIV-1 Reverse Transcriptase Inhibitors. 1. Synthesis and Basic Structure-Activity Relationship Studies of PETT Analogs

3. Rational design of N-[2-(2,5-dimethoxyphenylethyl)]-N′-[2-(5-bromopyridyl)]-thiourea (HI-236) as a potent non-nucleoside inhibitor of drug-resistant human immunodeficiency virus

4. Structure-based design of N-[2-(1-piperidinylethyl)]-N′-[2-(5-bromopyridyl)]-thiourea and N-[2-(1-piperazinylethyl)]-N′-[2-(5-bromopyridyl)]-thiourea as potent non-nucleoside inhibitors of HIV-1 reverse transcriptase

Cited by 50 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Design, Synthesis and Evaluation of Thiourea Derivatives as Antimicrobial and Antiviral Agents;Letters in Drug Design & Discovery;2019-05-24

2. The Lipophilic Bullet Hits the Targets: Medicinal Chemistry of Adamantane Derivatives;Chemical Reviews;2013-02-25

3. ChemInform Abstract: N-[2-(1-Cyclohexenyl)ethyl]-N′-[2-(5-bromopyridyl)]-thiourea and N′-[2-(1-Cyclohexenyl)ethyl]-N′-[2-(5-chloropyridyl)]-thiourea as Potent Inhibitors of Multidrug-Resistant Human Immunodeficiency Virus-1.;ChemInform;2010-06-12

4. Identification of Hits as Matrix-2 Protein Inhibitors through the Focused Screening of a Small Primary Amine Library;Journal of Medicinal Chemistry;2010-04-15

5. Novel modifications in the series of O-(2-phthalimidoethyl)-N-substituted thiocarbamates and their ring-opened congeners as non-nucleoside HIV-1 reverse transcriptase inhibitors;European Journal of Medicinal Chemistry;2009-04