Oxo-piperazine Derivatives of N-Arylpiperazinones as Inhibitors of Farnesyltransferase-Reference-Cited by-同舟云学术

Oxo-piperazine Derivatives of N-Arylpiperazinones as Inhibitors of Farnesyltransferase

Published:2001-02 Issue:4 Volume:11 Page:537-540
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Dinsmore Christopher J,Bergman Jeffrey M,Wei Donna D,Zartman C.Blair,Davide Joseph P,Greenberg Ian B,Liu Dongming,O'Neill Timothy J,Gibbs Jackson B,Koblan Kenneth S,Kohl Nancy E,Lobell Robert B,Chen I-Wu,McLoughlin Debra A,Olah Timothy V,Graham Samuel L,Hartman George D,Williams Theresa M

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference26 articles.

1. Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity.

2. Ras Protein Farnesyltransferase: A Strategic Target for Anticancer Therapeutic Development

3. Ras C-terminal processing enzymes—New drug targets?

4. THE POTENTIAL OF FARNESYLTRANSFERASE INHIBITORS AS CANCER CHEMOTHERAPEUTICS

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