Synthesis, evaluation, and crystallographic analysis of L-371,912: A potent and selective active-site thrombin inhibitor-Reference-Cited by-同舟云学术

Synthesis, evaluation, and crystallographic analysis of L-371,912: A potent and selective active-site thrombin inhibitor

Published:1997-01 Issue:1 Volume:7 Page:67-72
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Lyle Terry A.,Chen Zhongguo,Appleby Sandra D.,Freidinger Roger M.,Gardell Stephen J.,Lewis S.Dale,Li Ying,Lyle Elizabeth A.,Lynch Joseph J.,Mulichak Anne M.,Ng Assunta S.,Naylor-Olsen Adel M.,Sanders William M.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference13 articles.

1. Synthetic low-molecular weight thrombin inhibitors: molecular design and pharmacological profile

2. Small-molecule inhibitors of thrombin

3. The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment.

4. Proc. 14th Amer. Peptide Symp.;Brady,1995

5. Amide and α-keto carbonyl inhibitors of thrombin based on arginine and lysine: Synthesis, stability and biological characterization

Cited by 49 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Mechanism and inhibition kinetics of peptide P13 as thrombin inhibitor;International Journal of Biological Macromolecules;2020-05

2. Design of Serine Protease Inhibitors;Structure-Based Design of Drugs and Other Bioactive Molecules;2015-05-29

3. Liporetro-D-peptides - A novel class of highly selective thrombin inhibitors;Thrombosis Research;2012-04

4. ChemInform Abstract: Synthesis, Evaluation, and Crystallographic Analysis of L-371,912: A Potent and Selective Active-Site Thrombin Inhibitor.;ChemInform;2010-08-04

5. Maximum Common Binding Modes (MCBM): Consensus Docking Scoring Using Multiple Ligand Information and Interaction Fingerprints;Journal of Chemical Information and Modeling;2008-01-23