Glucose-insensitivity induced by Ca2+ toxicity in islet β-cells and its prevention by PACAP
Author:
Publisher
Elsevier BV
Subject
Cellular and Molecular Neuroscience,Endocrinology,Physiology,Biochemistry
Reference23 articles.
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2. Perspectives on pituitary adenylate cyclase activating polypeptide (PACAP) in the neuroendocrine, endocrine, and nervous systems;Arimura;Jpn J Physiol,1998
3. Prolonged exposure of human pancreatic islets to high glucose concentrations in vitro impairs the β-cell function;Eizirik;J Clin Invest,1992
4. Glucose and tolbutamide induce apoptosis in pancreatic β-cells a process dependent on intracellular CA2+ concentration;Efanova;J Biol Chem,1998
5. Pituitary adenylate cyclase-activating polypeptide (PACAP);Fridolf;Cell Tissue and Res,1992
Cited by 9 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Inhibition of Calcium Influx Reduces Dysfunction and Apoptosis in Lipotoxic Pancreatic β-Cells via Regulation of Endoplasmic Reticulum Stress;PLOS ONE;2015-07-06
2. The PACAP-Regulated Gene Selenoprotein T Is Abundantly Expressed in Mouse and Human β-Cells and Its Targeted Inactivation Impairs Glucose Tolerance;Endocrinology;2013-10-01
3. Intra-Islet PACAP Protects Pancreatic β-Cells Against Glucotoxicity and Lipotoxicity;Journal of Molecular Neuroscience;2010-05-12
4. Pituitary adenylate cyclase-activating polypeptide attenuates streptozotocin-induced apoptotic death of RIN-m5F cells through regulation of Bcl-2 family protein mRNA expression;FEBS Journal;2008-09-29
5. Sub-chronic stimulation of glucocorticoid receptor impairs and mineralocorticoid receptor protects cytosolic Ca2+ responses to glucose in pancreatic β-cells;Journal of Endocrinology;2008-03-04
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