Thymic skewing of the CD4/CD8 ratio maps with the T-cell receptor α-chain locus

Author:

Sim Bee-Cheng,Aftahi Najla,Reilly Christina,Bogen Bjarne,Schwartz Ronald H.,Gascoigne Nicholas R.J.,Lo David

Publisher

Elsevier BV

Subject

General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology

Reference28 articles.

1. Asymmetric signaling requirements for thymocyte commitment to the CD4+ versus CD8+ T cell lineages: a new perspective on thymic commitment and selection;Suzuki;Immunity,1995

2. Precommitment of CD4+CD8+ thymocytes to either CD4 or CD8 lineages;Crompton;Proc Natl Acad Sci USA,1993

3. Functional commitment to helper T cell lineage precedes positive selection and is independent of T cell receptor MHC specificity;Corbella;Immunity,1994

4. Positive selection of thymocytes;Jameson;Annu Rev Immunol,1995

5. The T cell receptor Vα11 gene family. Analysis of allelic sequence polymorphism and demonstration of Jα-region dependent recognition by allele-specific antibodies;Jameson;J Immunol,1991

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