Penetration of 5-fluorouracil and prodrugs across the intestine of the albino rabbit: Evidence for shift in absorption site from the upper to the lower region of the gastrointestinal tract by prodrugs

Author:

Buur Anders,Yamamoto Akira,Lee Vincent H.L.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference43 articles.

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2. Clinical pharmacology of 5-fluorouracil;Diasio;Clin. Pharmacokin.,1989

3. Fluorouracil therapy in patients: a pharmacokinetic comparison of various rates and routes of administration;Christophidis;Clin. Pharmacokin.,1978

4. Prodrugs of 5-fluorouracil. I. Hydrolysis kinetics and physicochemical properties of various N-acyl derivatives of 5-fluorouracil;Buur;Int. J. Pharm.,1984

5. Prodrugs of 5-fluorouracil. II. Hydrolysis kinetics, bioactivation, solubility and lipophilicity of N-alkoxycarbonyl derivatives of 5-fluorouracil;Buur;Arch. Pharm. Chemi., Sci. Ed.,1984

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5. First-pass Metabolism of 5-Fluorouracil in Rats;Journal of Pharmacy and Pharmacology;1998-09

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