Mechanism of action of IC 100, a humanized IgG4 monoclonal antibody targeting apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC)-Reference-Cited by-同舟云学术

Mechanism of action of IC 100, a humanized IgG4 monoclonal antibody targeting apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC)

Published:2023-01 Issue: Volume:251 Page:27-40
ISSN:1931-5244
Container-title:Translational Research
language:en
Short-container-title:Translational Research

Author:

de Rivero Vaccari Juan Pablo,Mim Carsten,Hadad Roey,Cyr Brianna,Stefansdottir Thorunn Anna,Keane Robert W.

Publisher

Elsevier BV

Subject

Biochemistry (medical),Public Health, Environmental and Occupational Health,General Medicine,Physiology (medical)

Reference52 articles.

1. Development of therapeutic antibodies for the treatment of diseases;Lu;J Biomed Sci,2020

2. Replacing the complementarity-determining regions in a human antibody with those from a mouse;Jones;Nature,1986

3. In vivo electroporation and non-protein based screening assays to identify antibodies against native protein conformations;Daftarian;Hybridoma (Larchmt),2011

4. Targeted protein degradation using intracellular antibodies and its application to neurodegenerative disease;Benn;Semin Cell Dev Biol,2021

5. Acute and rapid degradation of endogenous proteins by Trim-Away;Clift;Nat Protoc,2018

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