Opioids, stress and addiction: From stress-induced analgesia to opioid heterodimers with extraordinary analgesic efficacy and without the side effects of traditional opioids

Author:

Cataldo GiuseppeORCID,Simone Donald A.,Bodnar Richard J

Funder

NIH

Publisher

Elsevier BV

Reference195 articles.

1. Chronic pain and chronic stress: two sides of the same coin?;Abdallah;Chronic. Stress. (Thousand. Oaks),2017

2. MDAN-21: a bivalent opioid ligand containing mu-agonist and delta-antagonist pharmacophores and its effects in rhesus monkeys;Aceto;Int. J. Med. Chem.,2012

3. Emerging field of biased opioid agonists;Aggarwal;Anesthesiol. Clin.,2023

4. Inhibition of inflammatory and neuropathic pain by targeting a mu opioid receptor/chemokine receptor5 heteromer (MOR-CCR5);Akgün;J. Med. Chem.,2015

5. Ligands that interact with putative MOR-mGluR5 heteromer in mice with inflammatory pain produce potent antinociception;Akgün;Proc. Natl. Acad. Sci. (USA),2013

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