Actinoplanes utahensis ZJB-08196 fed-batch fermentation at elevated osmolality for enhancing acarbose production

Author:

Wang Ya-Jun,Liu Li-Ling,Wang Yuan-Shan,Xue Ya-Ping,Zheng Yu-Guo,Shen Yin-Chu

Funder

China National Special Program for Key Science and Technology

973 Program

Special Program for Key Science and Technology of Zhejiang

National Scientific Foundation of China

Publisher

Elsevier BV

Subject

Waste Management and Disposal,Renewable Energy, Sustainability and the Environment,General Medicine,Environmental Engineering,Bioengineering

Reference27 articles.

1. Beunink, J., Schedel, M., Steiner, U., 2000. Osmotically controlled fermentation process for the preparation of acarbose. US Patent 6,130,072.

2. Disaccharides as a new class of nonaccumulated osmoprotectants for Sinorhizobium meliloti;Blanco;Appl. Environ. Microb.,1999

3. Intracellular organic osmolytes: function and regulation;Burg;J. Biol. Chem.,2008

4. Acarbose for prevention of type 2 diabetes mellitus: the STOPNIDDM randomised trial;Chiasson;Lancet,2002

5. Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impaired glucose tolerance – the STOP-NIDDM ttrial;Chiasson;J. Am. Med. Assoc.,2003

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