A recombinant prime, peptide boost vaccination strategy can focus the immune response on to more than one epitope even though these may not be immunodominant in the complex immunogen

Author:

Davis David,Morein Bror,Åkerblom Lennart,Lövgren-Bengtsson Karin,van Gils Mariëlle E.,Bogers Willy M.J.M.,Teeuwsen Vera J.P.,Heeney Jonathan L.

Publisher

Elsevier BV

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,General Veterinary,General Immunology and Microbiology,Molecular Medicine

Reference43 articles.

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2. Immunization of chimpanzees confers protection against challenge with human immunodeficiency virus;Girard,1991

3. Vaccine-induced protection of chimpanzees against infection by a heterologous human immunodeficiency virus type 1;Girard;Journal of Virology,1995

4. Heeney, J.L., Teeuwsen, V., van Gils, M., Bogers, W., De Guili Morghen, C., Ghioni, C., Gimelli, M., Morein, B., Åkerblom, L. and Davis, D. HIV-1 vaccine efficacy by induction of TH1 and TH2 immunity (submitted for publication, Science)

5. Effect of dose and immunization schedule on immune response of baboons to recombinant glycoprotein gp120 of HIV-1;Anderson;Journal of Infectious Diseases,1989

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