Simultaneous determination of p-hydroxylated and dihydrodiol metabolites of phenytoin in urine by high-performance liquid chromatography
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,General Medicine,Biochemistry,Analytical Chemistry
Reference22 articles.
1. Improved isocratic liquid-chromatographic simultaneous measurement of phenytoin, phenobarbital, primidone, carbamazepine, ethosuximide, and N-desmethylmethsuximide in serum.
2. Determination of 5-(3,4-Dihydroxy-1,5-cyclohexadien-1-yl)-5-phenylhydantoin (Dihydrodiol) and Quantitative Studies of Phenytoin Metabolism in Man
3. Determination of 5-(P-Hydroxyphenyl)-5-Phenylhydantoin and Studies Relating to the Disposition of Phenytoin in Man
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1. Granulysin-Based Lymphocyte Activation Test for Evaluating Drug Causality in Antiepileptics-Induced Severe Cutaneous Adverse Reactions;Journal of Investigative Dermatology;2021-06
2. Phenytoin – An anti-seizure drug: Overview of its chemistry, pharmacology and toxicology;Food and Chemical Toxicology;2020-08
3. Role of cytochrome P450-mediated metabolism and involvement of reactive metabolite formations on antiepileptic drug-induced liver injuries;The Journal of Toxicological Sciences;2018
4. Effects of duration of phenytoin administration on mRNA expression of cytochrome P450 and P-glycoprotein in the liver and small intestine of rats;Asian Journal of Pharmaceutical Sciences;2016-10
5. Role of cytochrome P450-mediated metabolism and identification of novel thiol-conjugated metabolites in mice with phenytoin-induced liver injury;Toxicology Letters;2015-01
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