Synthesis of N-benzyl-3-(S)-(+)-(4-fluorophenyl)-1,4-oxazin-2-one via a crystallisation induced asymmetric transformation-Reference-Cited by-同舟云学术

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Synthesis of N-benzyl-3-(S)-(+)-(4-fluorophenyl)-1,4-oxazin-2-one via a crystallisation induced asymmetric transformation

Published:1997-02 Issue:3 Volume:8 Page:447-450
ISSN:0957-4166
Container-title:Tetrahedron: Asymmetry
language:en
Short-container-title:Tetrahedron: Asymmetry

Author:

Alabaster Ramon J.,Gibson Andrew W.,Johnson Simon A.,Edwards John S.,Cottrell Ian F.

Publisher

Elsevier BV

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Catalysis

Reference15 articles.

1. Dorn, C. P.; Hale, J. J.; MacCoss, M.; Mills, S. G.; Ladduwahetty, T.; Shah, S. K. Eur. Pat. Appl. E.P. 577394 A1, 1994.

2. Synthesis and reaction of optically active morpholinones

3. The asymmetric synthesis of .alpha.-amino acids. Electrophilic azidation of chiral imide enolates, a practical approach to the synthesis of (R)- and (S)-.alpha.-azido carboxylic acids

4. An Efficient and Practical Synthesis of L-α-Amino Acids Using (R)-Phenylglycinol as a Chiral Auxiliary

5. Crystallisation induced resolution of 4-fluorophenylglycine

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2. Efficient Synthesis of (S)-3-(4-Fluorophenyl)morpholin-2-one, a Key Chiral Intermediate of Aprepitant;Synthetic Communications;2015-06-19

3. Reactions of glycidyl derivatives with ambident nucleophiles; part 2: amino acid derivatives;Beilstein Journal of Organic Chemistry;2007-09-27

4. An Alternative Approach to Achieve Enantiopure (3S)-4-Benzyl-3- (4-fluorophenyl)morpholin-2-one: A Key Intermediate of Aprepitant, an NK1 Receptor Antagonist;Organic Process Research & Development;2007-05-01

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