A novel achiral seco-cyclopropylpyrido[e]indolone (CPyI) analog of CC-1065 and the duocarmycins: Synthesis, DNA interactions, in vivo anticancer and anti-parasitic evaluation-Reference-Cited by-同舟云学术

A novel achiral seco-cyclopropylpyrido[e]indolone (CPyI) analog of CC-1065 and the duocarmycins: Synthesis, DNA interactions, in vivo anticancer and anti-parasitic evaluation

Published:2010-07 Issue:14 Volume:18 Page:5016-5024
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Chavda Sameer,Babu Balaji,Yanow Stephanie K.,Jardim Armando,Spithill Terry W.,Kiakos Konstantinos,Kluza Jerome,Hartley John A.,Lee Moses

Funder

Cancer Research UK

Natural Science and Engineering Research Council of Canada

Fonds québécois de la recherche sur la nature et les technologies

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference73 articles.

1. Synthesis, DNA-binding properties, and antitumor activity of novel distamycin derivatives

2. Structure and activity relationship of several novel CC-1065 analogs

3. Adozelesin, a selected lead among cyclopropylpyrroloindole analogs of the DNA-binding antibiotic, CC-1065

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