Potent antitumor 9-anilinoacridines bearing an alkylating N-mustard residue on the anilino ring: synthesis and biological activity

Author:

Bacherikov Valeriy A.,Chou Ting-Chao,Dong Hua-Jin,Zhang Xiuguo,Chen Ching-Huang,Lin Yi-Wen,Tsai Tsong-Jen,Lee Rong-Zau,Liu Leroy F.,Su Tsann-Long

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference43 articles.

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2. Mechanisms of DNA sequence-selective alkylation of guanine-N7 positions by nitrogen mustards;Kohn;Nucleic Acid Res.,1987

3. The molecular electrostatic potential of the B-DNA helix. II. The region of the adenine-thymine base pair;Perehia;Theor. Chim. Acta,1979

4. The chemical effects of nucleic acid alkylation, and their relationship to mutagenesis and carcinogenesis;Singer;Prog. Nucl. Acids Res. Mol. Biol.,1975

5. Relationship between functionality and genetic toxicology of selected DNA-damaging agents;Brendel;Mutat. Res.,1984

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