Discovery of potent and selective PARP-1 and PARP-2 inhibitors: SBDD analysis via a combination of X-ray structural study and homology modeling-Reference-Cited by-同舟云学术

Discovery of potent and selective PARP-1 and PARP-2 inhibitors: SBDD analysis via a combination of X-ray structural study and homology modeling

Published:2006-03 Issue:5 Volume:14 Page:1378-1390
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Ishida Junya,Yamamoto Hirofumi,Kido Yoshiyuki,Kamijo Kazunori,Murano Kenji,Miyake Hiroshi,Ohkubo Mitsuru,Kinoshita Takayoshi,Warizaya Masaichi,Iwashita Akinori,Mihara Kayoko,Matsuoka Nobuya,Hattori Kouji

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference26 articles.

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3. Poly(ADP-ribose)polymerase null mouse cells synthesize ADP-ribose polymerase;Shieh;J. Biol. Chem.,1998

4. PARP-2, a novel mammalian DNA damage-dependent poly(ADP-ribose)polymerase;Ame;J. Biol. Chem.,1999

5. Inhibitor and NAD+ binding to poly(ADP-ribose) polymerase as derived from crystal structures and homology modeling;Ruf;Biochemistry,1998

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