Novel 3-aroylpyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides 8-substituted, ligands at GABAA/benzodiazepine receptor complex: Synthesis, pharmacological and molecular modeling studies-Reference-Cited by-同舟云学术

Novel 3-aroylpyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides 8-substituted, ligands at GABAA/benzodiazepine receptor complex: Synthesis, pharmacological and molecular modeling studies

Published:2008-04 Issue:8 Volume:16 Page:4471-4489
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Guerrini Gabriella,Ciciani Giovanna,Cambi Giovanni,Bruni Fabrizio,Selleri Silvia,Melani Fabrizio,Montali Marina,Martini Claudia,Ghelardini Carla,Norcini Monica,Costanzo Annarella

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference59 articles.

1. Positioning of the -subunit isoforms confers a functional signature to -aminobutyric acid type A receptors

2. GABA-based therapeutic approaches: GABAA receptor subtype functions

3. α-Subunit selective modulators of GABAAreceptor function as CNS therapeutics

4. Development of Subtype Selective GABAA Modulators

5. Analysis of GABAA Receptor Function and Dissection of the Pharmacology of Benzodiazepines and General Anesthetics Through Mouse Genetics

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