LipE guided discovery of isopropylphenyl pyridazines as pantothenate kinase modulators-Reference-Cited by-同舟云学术

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LipE guided discovery of isopropylphenyl pyridazines as pantothenate kinase modulators

Published:2021-12 Issue: Volume:52 Page:116504
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Sharma Lalit Kumar,Yun Mi Kyung,Subramanian Chitra,Tangallapally Rajendra,Jackowski Suzanne,Rock Charles O.,White Stephen W.,Lee Richard E.

Funder

National Institutes of Health

American Lebanese Syrian Associated Charities

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference25 articles.

1. Coenzyme A: back in action;Leonardi;Prog Lipid Res,2005

2. Regulation of coenzyme A biosynthesis;Jackowski;J Bacteriol,1981

3. A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome;Zhou;Nat Genet,2001

4. Feedback regulation of murine pantothenate kinase 3 by coenzyme A and coenzyme A thioesters;Zhang;J Biol Chem,2005

5. The murine pantothenate kinase (Pank1) gene encodes two differentially regulated pantothenate kinase isozymes;Rock;Gene,2002

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1. Development of Brain Penetrant Pyridazine Pantothenate Kinase Activators;Journal of Medicinal Chemistry;2024-08-13

2. An update on lipophilic efficiency as an important metric in drug design;Expert Opinion on Drug Discovery;2024-06-26

3. The pyridazine heterocycle in molecular recognition and drug discovery;Medicinal Chemistry Research;2023-03-15

4. Cyanopyridine as a privileged scaffold in drug discovery;Privileged Scaffolds in Drug Discovery;2023

5. Relief of CoA sequestration and restoration of mitochondrial function in a mouse model of propionic acidemia;Journal of Inherited Metabolic Disease;2022-11-03

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