Rationally designed hecogenin thiosemicarbazone analogs as novel MEK inhibitors for the control of breast malignancies-Reference-Cited by-同舟云学术

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Rationally designed hecogenin thiosemicarbazone analogs as novel MEK inhibitors for the control of breast malignancies

Published:2017-12 Issue:24 Volume:25 Page:6297-6312
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Elsayed Heba E.,Ebrahim Hassan Y.,Haggag Eman G.,Kamal Amel M.,El Sayed Khalid A.

Funder

Ministry of Higher Education

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference47 articles.

1. Evidence for the Involvement of Descending Pain-Inhibitory Mechanisms in the Antinociceptive Effect of Hecogenin Acetate

2. Effects of hecogenin and its possible mechanism of action on experimental models of gastric ulcer in mice

3. Anti-Inflammatory Activity of Aqueous Extracts and Steroidal Sapogenins ofAgave americana

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1. Hecogenin alleviates LPS-induced osteolysis via regulating pyroptosis and ROS involved Nrf2 activation;Biomedicine & Pharmacotherapy;2024-08

2. Triphenylphosphonium-linked derivative of hecogenin with enhanced antiproliferative activity: Design, synthesis, and biological evaluation;Bioorganic Chemistry;2024-04

3. Quinoline-based Anti-oncogenic Molecules: Synthesis and Biological Evaluation;Medicinal Chemistry;2023-11

4. Cytotoxicity of copper(I) complexes containing indole‐based thiosemicarbazones and triphenylphosphine;ChemistrySelect;2023-08

5. Structure-based identification of potential inhibitors of ribosomal protein S6 kinase 1, targeting cancer therapy: a combined docking and molecular dynamics simulations approach;Journal of Biomolecular Structure and Dynamics;2023-06-26

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