Design, synthesis, structure–activity relationship, and in vivo activity of azabicyclic aryl amides as α7 nicotinic acetylcholine receptor agonists

Author:

Walker Daniel P.,Wishka Donn G.,Piotrowski David W.,Jia Shaojuan,Reitz Steven C.,Yates Karen M.,Myers Jason K.,Vetman Tatiana N.,Margolis Brandon J.,Jacobsen E. Jon,Acker Brad A.,Groppi Vincent E.,Wolfe Mark L.,Thornburgh Bruce A.,Tinholt Paula M.,Cortes-Burgos Luz A.,Walters Rodney R.,Hester Matthew R.,Seest Eric P.,Dolak Lester A.,Han Fusen,Olson Barbara A.,Fitzgerald Laura,Staton Brian A.,Raub Thomas J.,Hajos Mihaly,Hoffmann William E.,Li Kai S.,Higdon Nicole R.,Wall Theron M.,Hurst Raymond S.,Wong Erik H.F.,Rogers Bruce N.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference72 articles.

1. Nicotinic Receptors in the Brain Links between Molecular Biology and Behavior

2. Overview of nicotinic receptors and their roles in the central nervous system

3. Neuronal Nicotinic Receptors: Pharmacology and Therapeutic Opportunities,1999

4. Handbook of Experimental Pharmacology: Neuronal Nicotinic Receptors,2000

5. Neuronal nicotinic acetylcholine receptors: from the gene to the disease

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