Discovery of a novel 5-carbonyl-1H-imidazole-4-carboxamide class of inhibitors of the HIV-1 integrase–LEDGF/p75 interaction-Reference-Cited by-同舟云学术

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Discovery of a novel 5-carbonyl-1H-imidazole-4-carboxamide class of inhibitors of the HIV-1 integrase–LEDGF/p75 interaction

Published:2013-10 Issue:19 Volume:21 Page:5963-5972
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Serrao Erik,Xu Zhong-Liang,Debnath Bikash,Christ Frauke,Debyser Zeger,Long Ya-Qiu,Neamati Nouri

Funder

NIH/NIAID

Campbell foundation (N.N.)

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference53 articles.

1. HIV entry inhibitors and their potential in HIV therapy

2. HIV-1 reverse transcriptase inhibitors

3. Current status of antiretroviral therapy

4. Raltegravir: the first HIV-1 integrase strand transfer inhibitor in the HIV armamentarium

5. Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection

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