Modular synthesis and biological activity of pyridyl-based analogs of the potent Class I Histone Deacetylase Inhibitor Largazole-Reference-Cited by-同舟云学术

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Modular synthesis and biological activity of pyridyl-based analogs of the potent Class I Histone Deacetylase Inhibitor Largazole

Published:2015-08 Issue:15 Volume:23 Page:5061-5074
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Clausen Dane J.,Smith William B.,Haines Brandon E.,Wiest Olaf,Bradner James E.,Williams Robert M.

Funder

National Institutes of Health

Colorado State University Cancer Supercluster

NIH

National Cancer Institute

Burroughs-Wellcome Foundation

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference30 articles.

1. Structure and Activity of Largazole, a Potent Antiproliferative Agent from the Floridian Marine Cyanobacterium Symploca sp.

2. Structure and Activity of Largazole, a Potent Antiproliferative Agent from the Floridian Marine CyanobacteriumSymplocasp.

3. Discovery, biological activity, synthesis and potential therapeutic utility of naturally occurring histone deacetylase inhibitors

4. Largazole: From discovery to broad-spectrum therapy

5. Synthetic Routes and Biological Evaluation of Largazole and Its Analogues as Potent Histone Deacetylase Inhibitors

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