In situ click chemistry-based discovery of 1,2,3-triazole-derived diarylpyrimidines as novel HIV-1 NNRTIs by exploiting the tolerant region I in binding pocket-Reference-Cited by-同舟云学术

In situ click chemistry-based discovery of 1,2,3-triazole-derived diarylpyrimidines as novel HIV-1 NNRTIs by exploiting the tolerant region I in binding pocket

Published:2023-12 Issue: Volume:96 Page:117484
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Sun Yanying,Feng Da,Zhou Zhenzhen,Zhang Tao,De Clercq Erik,Pannecouque Christophe,Kang Dongwei^ORCID,Zhan Peng,Liu Xinyong^ORCID

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference31 articles.

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5. Thermodynamics of HIV-1 reverse transcriptase in action elucidates the mechanism of action of non-nucleoside inhibitors;Bec;J Am Chem Soc,2013

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