Synthesis and molecular modeling of 1H-pyrrolopyrimidine-2,4-dione derivatives as ligands for the α1-adrenoceptors-Reference-Cited by-同舟云学术

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Synthesis and molecular modeling of 1H-pyrrolopyrimidine-2,4-dione derivatives as ligands for the α1-adrenoceptors

Published:2011-09 Issue:17 Volume:19 Page:5260-5276
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Pittalà Valeria,Siracusa Maria A.,Modica Maria N.,Salerno Loredana,Pedretti Alessandro,Vistoli Giulio,Cagnotto Alfredo,Mennini Tiziana,Romeo Giuseppe

Funder

Italian M. I. U. R.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference56 articles.

1. .alpha.- and .beta.-Adrenoceptors: From the Gene to the Clinic. Part 1. Molecular Biology and Adrenoceptor Subclassification

2. .alpha.- and .beta.-Adrenoceptors: From the Gene to the Clinic. 2. Structure-Activity Relationships and Therapeutic Applications

3. Recent Advances in α1-Adrenoreceptor Antagonists as Pharmacological Tools and Therapeutic Agents

4. Novel antagonists for α1-adrenoceptor subtypes

5. The α1-adrenergic receptors: diversity of signaling networks and regulation

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