Efficient synthesis and antitumor evaluation of 4-aminomethyl-N-arylpyrazoles: Discovery of potent and selective agents for ovarian cancer-Reference-Cited by-同舟云学术

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Efficient synthesis and antitumor evaluation of 4-aminomethyl-N-arylpyrazoles: Discovery of potent and selective agents for ovarian cancer

Published:2021-01 Issue: Volume:29 Page:115835
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

da Silva Michael J.V.,Jacomini Andrey P.,Figueiredo Mariana C.,Back Davi F.,Foglio Mary A.,Ruiz Ana L.T.G.,Paula Fávero R.,Rosa Fernanda A.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference42 articles.

1. Ovarian cancer statistics, 2018

2. Cyclin-dependent protein serine/threonine kinase inhibitors as anticancer drugs

3. Recent development of CDK inhibitors: An overview of CDK/inhibitor co-crystal structures

4. Synthesis, biological evaluation, and molecular docking studies of N-((1,3-diphenyl-1H-pyrazol-4-yl)methyl)aniline derivatives as novel anticancer agents

5. Recent advances in bioactive pyrazoles

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1. N-Arylpyrazole based Scaffolds: Synthesis and biological applications;Journal of Saudi Chemical Society;2024-05

2. The anticancer and EGFR-TK/CDK-9 dual inhibitory potentials of new synthetic pyranopyrazole and pyrazolone derivatives: X-ray crystallography, in vitro , and in silico mechanistic investigations;Journal of Biomolecular Structure and Dynamics;2023-01-20

3. Antileishmanial activity of 3,4,5-trisubstituted isoxazoles by interaction with Leishmania amazonensis plasma membrane;Journal of Molecular Structure;2022-02

4. Discovery of 1,3,4,5-tetrasubstituted pyrazoles as anti-trypanosomatid agents: Identification of alterations in flagellar structure of L. amazonensis;Bioorganic Chemistry;2021-09

5. Synthesis and Antiprotozoal Profile of 3,4,5‐Trisubstituted Isoxazoles;ChemistryOpen;2021-07-30

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