Design, synthesis and biological evaluation of small molecule inhibitors of CD4-gp120 binding based on virtual screening-Reference-Cited by-同舟云学术

Design, synthesis and biological evaluation of small molecule inhibitors of CD4-gp120 binding based on virtual screening

Published:2011-01 Issue:1 Volume:19 Page:91-101
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

LaLonde Judith M.,Elban Mark A.,Courter Joel R.,Sugawara Akihiro,Soeta Takahiro,Madani Navid,Princiotto Amy M.,Kwon Young Do,Kwong Peter D.,Schön Arne,Freire Ernesto,Sodroski Joseph,Smith Amos B.

Funder

NIH

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference45 articles.

1. Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

2. Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDS

3. Functional Regions of the Envelope Glycoprotein of Human Immunodeficiency Virus Type 1

4. The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

5. Conformational changes induced in the human immunodeficiency virus envelope glycoprotein by soluble CD4 binding.

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