Design, synthesis, and evaluation of Leu∗Ala hydroxyethylene-based non-peptide β-secretase (BACE) inhibitors-Reference-Cited by-同舟云学术

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Design, synthesis, and evaluation of Leu∗Ala hydroxyethylene-based non-peptide β-secretase (BACE) inhibitors

Published:2006-07 Issue:13 Volume:14 Page:4535-4551
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Xiao Kun,Li Xin,Li Jingya,Ma Lanping,Hu Bin,Yu Haiping,Fu Yan,Wang Rui,Ma Zeqiang,Qiu Beiying,Li Jia,Hu Dingyu,Wang Xin,Shen Jingkang

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference32 articles.

1. The Cholinergic Hypothesis of Geriatric Memory Dysfunction

2. β-Secretase inhibition for the treatment of Alzheimer's disease – promise and challenge

3. Chapter 53: Brain selective inhibition of acetylcholinesterase: a novel approach to therapy for Alzheimer's disease

4. Secretase Targets for Alzheimer's Disease: Identification and Therapeutic Potential

5. β-Secretase as a Therapeutic Target for Inhibitor Drugs

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3. A new insight into computational molecular design: A case study on BACE-1 inhibitors;Journal of Computational Methods in Sciences and Engineering;2014-10-08

4. Cognitive Enhancers (Nootropics). Part 2: Drugs Interacting with Enzymes;Journal of Alzheimer's Disease;2013-01-10

5. Ab initio modeling of a potent isophthalamide-based BACE-1 inhibitor: amino acid decomposition analysis;Medicinal Chemistry Research;2012-11-21

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