Design, synthesis, and biological evaluation of amide imidazole derivatives as novel metabolic enzyme CYP26A1 inhibitors-Reference-Cited by-同舟云学术

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Design, synthesis, and biological evaluation of amide imidazole derivatives as novel metabolic enzyme CYP26A1 inhibitors

Published:2015-10 Issue:20 Volume:23 Page:6763-6773
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Sun Bin,Liu Kai,Han Jing,Zhao Li-yu,Su Xiao,Lin Bin,Zhao Dong-Mei,Cheng Mao-Sheng

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference37 articles.

1. Retinoids in cancer therapy.

2. Retinoids regulate stem cell differentiation

3. Phase I evaluation of all-trans-retinoic acid in adults with solid tumors.

4. Increasing the intracellular availability of all-trans retinoic acid in neuroblastoma cells

5. Regulation of a highly specific retinoic acid-4-hydroxylase (CYP26A1) enzyme and all-trans-retinoic acid metabolism in human intestinal, liver, endothelial, and acute promyelocytic leukemia cells

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4. Metformin reduces hepatocarcinogenesis by inducing downregulation of Cyp26a1 and CD8⁺ T cells;Clinical and Translational Medicine;2023-11

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