Design and synthesis of potent substrate-based inhibitors of the Trypanosoma cruzi dihydroorotate dehydrogenase-Reference-Cited by-同舟云学术

Design and synthesis of potent substrate-based inhibitors of the Trypanosoma cruzi dihydroorotate dehydrogenase

Published:2017-02 Issue:4 Volume:25 Page:1465-1470
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Inaoka Daniel Ken,Iida Maiko,Hashimoto Satoshi,Tabuchi Toshiyuki,Kuranaga Takefumi,Balogun Emmanuel Oluwadare,Honma Teruki,Tanaka Akiko,Harada Shigeharu,Nara Takeshi,Kita Kiyoshi,Inoue Masayuki

Funder

Targeted Proteins Research Program from MEXT

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference24 articles.

1. Chagas’ Disease

2. Chagas Disease (American Trypanosomiasis), Fact Sheet No. 340; World Health Organization: Geneva, Switzerland, updated March 2016.

3. The challenge of Chagas' disease chemotherapy: An update of drugs assayed against Trypanosoma cruzi

4. Pyrimidine Nucleotide Biosynthesis in Animals: Genes, Enzymes, and Regulation of UMP Biosynthesis

5. Characterization of the dihydroorotate dehydrogenase as a soluble fumarate reductase in Trypanosoma cruzi

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