Synthesis and biological evaluation of 9-(5′,5′-difluoro-5′-phosphonopentyl)guanine derivatives for PNP-inhibitors-Reference-Cited by-同舟云学术

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Synthesis and biological evaluation of 9-(5′,5′-difluoro-5′-phosphonopentyl)guanine derivatives for PNP-inhibitors

Published:2006-03 Issue:5 Volume:14 Page:1660-1670
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Hikishima Sadao,Isobe Machiko,Koyanagi Satoru,Soeda Shinji,Shimeno Hiroshi,Shibuya Shiroshi,Yokomatsu Tsutomu

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference20 articles.

1. Purine nucleoside phosphorylases: properties, functions, and clinical aspects

2. Inhibition of purine nucleoside phosphokylase by 9-(phosphonoalkyl)hypoxanthines

3. Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors.

4. Synthesis Of 9-(1-Deoxy-1-phosphono-β-D-psicofuranosyl)-1,9-dihydro-6H-purin-6-one as a Potential Transition State Analog Inhibitor of Purine Nucleoside Phosphorylase

5. [[(Guaninylalkyl)phosphinico]methyl]phosphonic Acids. Multisubstrate Analog Inhibitors of Human Erythrocyte Purine Nucleoside Phosphorylase

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1. Synthetic Strategies toward Ortho-3-propanoate Substituted Aryl Phosphonates by Three-Component Coupling Reactions of Arynes, Phosphites, and Acrylates;The Journal of Organic Chemistry;2024-05-28

2. Perspectives and challenges in developing small molecules targeting purine nucleoside phosphorylase;European Journal of Medicinal Chemistry;2024-05

3. [3+2] Cycloaddition reactions of β-diazo-α,α-difluoromethylphosphonates with α,β-unsaturated esters;Journal of Fluorine Chemistry;2021-11

4. Multigram Synthesis of Difluoromethylene Phosphonic and Phosphinic Amides and Phosphine Oxides via Formal [2,3]-Sigmatropic Allyl Phosphite–Allylphosphonate Rearrangement;Synthesis;2021-08-04

5. Recent Advances in Synthesis of Difluoromethylene Phosphonates for Biological Applications;Advanced Synthesis & Catalysis;2021-02-11

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