(−)-Meptazinol–melatonin hybrids as novel dual inhibitors of cholinesterases and amyloid-β aggregation with high antioxidant potency for Alzheimer’s therapy-Reference-Cited by-同舟云学术

(−)-Meptazinol–melatonin hybrids as novel dual inhibitors of cholinesterases and amyloid-β aggregation with high antioxidant potency for Alzheimer’s therapy

Published:2015-07 Issue:13 Volume:23 Page:3110-3118
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Cheng Shaobing,Zheng Wei,Gong Ping,Zhou Qiang,Xie Qiong,Yu Lining,Zhang Peiyi,Chen Liangkang,Li Juan,Chen Jianxing,Chen Hailin,Chen Hongzhuan

Funder

National Natural Science Foundation of China

Shanghai Municipal Science and Technology Commission

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference51 articles.

1. ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models

2. The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics

3. Pharmacotherapies for Alzheimer's disease: Beyond cholinesterase inhibitors

4. New Tacrine–4-Oxo-4H-chromene Hybrids as Multifunctional Agents for the Treatment of Alzheimer’s Disease, with Cholinergic, Antioxidant, and β-Amyloid-Reducing Properties

5. Design and synthesis of novel 3-substituted-indole derivatives as selective H3 receptor antagonists and potent free radical scavengers

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